The Bills go to Lucas Oil Stadium this week and I’m interested to see a full game of Andrew Luck under center.

Luck’s Colts are 6-4 and are in line for a Wild Card spot with a month and a half left of football. He’s eighth in the NFL in passing yards and — while he’s had rookie moments — appears to be the real deal.

If Luck outplays Ryan Fitzpatrick this week — a definite possibility — it will be a stark contrast between what a real franchise quarterback can do and what the Bills have been getting from the lovable but inconsistent Fitzpatrick.

Bills GM Buddy Nix suggested earlier this month he’s already looking ahead to quarterbacks in this year’s draft. Fitz and the Bills edged rookie QBs Brandon Weeden and Ryan Tannehill this season, but if Luck sinks Buffalo’s playoff chances this weekend, he may sink any remaining hope in Fitzpatrick as well.

Picks:

Bills (+3) at Indianapolis — Colts

Oakland (+7½) at Cincinnati — Bengals

Pittsburgh (pick) at Cleveland — Cleveland

Denver at Kansas City (+10) — Denver

Tennessee at Jacksonville (+3) — Jacksonville

Minnesota (pick) at Chicago — Chicago

Atlanta at Tampa Bay (+1) — Atlanta

Seattle at Miami (+3) — Seattle

Baltimore at San Diego (+1) — Ravens

San Francisco at New Orleans (+1) — Saints

St. Louis (+2) at Arizona — Cardinals

Green Bay (+2½) at Giants — Packers

Carolina (+2½) at Philadelphia — Carolina*

Skurski 77-67-5 (6-4-1)
DiCesare 75-69-5 (6-5)
Graham 72-72-5 (3-7-1)
Sullivan 69-75-5 (5-5-1)
IAGS 66-78-5 (8-2-1)
Northrop 64-80-5 (3-7-1)
Gaughan 64-80-5 (6-4-1)

Last week:

Philadelphia (+3½) at Washington — Washington
Redskins 31-6. Win

Green Bay at Detroit (+3½) — Detroit
Packers 24-20. Loss

Arizona (+10) at Atlanta — Atlanta
Falcons 23-19. Loss

Tampa Bay at Carolina (+1½) — Tampa
Bucs 27-21. Win

Cleveland (+7½) at Dallas — Cleveland
Cowboys 23-20. Win

Jets (+3½) at St. Louis — St. Louis
Jets 27-13. Loss

Indianapolis (+9½) at New England — Indianapolis
Pats 59-24. Loss

Jacksonville (+15½) at Houston — Houston
Texans 43-37. Loss

Cincinnati at Kansas City (+3½) — Bengals
Bengals 28-6. Win

New Orleans at Oakland (+5) — New Orleans
Saints 38-17. Win

San Diego (+7½) at Denver — Denver
Broncos 30-23. Loss

Baltimore (+3½) at Pittsburgh — Baltimore*
Ravens 13-10. Win

Chicago (+3) at San Francisco — San Fran
49ers 32-7. Win

7-6